Advanced Methods in Molecular Biology

Course aim

To present the principles of a comprehensive range of basic biotechnology techniques and their application to deciphering the genetic composition of whole genomes, the molecular biology of major human diseases and the detection and monitoring of disease and biotherapy.

Course content

Eukaryote genes: structure, function and control; translation control. Genomics Genome projects (HUGO): large scale DNA sequencing, sequence analysis, gene mapping; ethical issues. Bioinformatic techniques: Nucleic acid databases, protein databases, internet resources for bioinformatics, sequence analysis software, chemical databases, molecular modelling. Diagnostic techniques: nucleic acid amplification and other technologies for mutation detection. Therapy for genetic diseases, cloning in animal cells and whole animals. Protein technology: two dimensional protein separation and microanalysis including amino acid analysis, micro-sequencing, mass spectrometer-based analyses. Diagnosis of diseases. Independent research project conducted within the controlled and supervised environment of the UniSA teaching laboratories. This will act as essential preparation for the subsequent independent research project to be conducted in research laboratory as part of the research elective project.

Textbook(s)

Nil

Prerequisite(s)

Common to all relevant programs
Subject Area & Catalogue Number	Course Name
BIOL 2057	Genes to Proteins
BIOL 2016	Genetics

Corequisite(s)

Nil

Teaching method

Component	Duration
INTERNAL, CITY EAST
Lecture	2 hours x 13 weeks
Practical	6 hours x 7 weeks
Computer Practical	2 hours x 7 weeks

Note: These components may or may not be scheduled in every study period. Please refer to the timetable for further details.

Assessment

Examination, Learning log/Journal, Test/Quiz

Fees

EFTSL*: 0.125
Commonwealth Supported program (Band 2)
To determine the fee for this course as part of a Commonwealth Supported program, go to:
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Fee-paying program for domestic and international students
International students and students undertaking this course as part of a postgraduate fee paying program must refer to the relevant program home page to determine the cost for undertaking this course.

Non-award enrolment
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* Equivalent Full Time Study Load. Please note: all EFTSL values are published and calculated at ten decimal places. Values are displayed to three decimal places for ease of interpretation.