Genes to Proteins

Course aim

To establish a basic understanding of the cellular pathways that produce molecules of biological importance, and to develop practical skills in selected methods for analysing these molecules.

Course content

Genes, structure, organisation, localization. Chromatin and modelling. Regulation of genes and relationship to transcription. Transcriptional control mechanisms. Transcription factors, basal transcription apparatus. Gene control at distance. RNA structure, splicing. mRNA production and stability. Translation, translation control. Protein folding mechanisms and structure. Protein distribution. Protein signalling. Protein degradation.
Analysing DNA. Understanding recombinant DNA and its relationship to cloning. Protein expression using plasmids. Vectors fro DNA. Protein expression systems. Mass spectrometry and nuclear magnetic resonance for protein and DNA analysis; chromatographic and electrophoretic methods for nucleic acid and protein separation and characterisation; X-Ray crystallography as it pertains to the structure of proteins and amino acids; DNA and protein microarrays, principles and current technologies.

Textbook(s)

Nil

Prerequisite(s)

Subject Area & Catalogue Number	Course Name
Group 1
BIOL 1012	Molecules to Tissues B
CHEM 1006	Chemistry 100
CHEM 1007	Chemistry 101
BIOL 1007	Molecules to Tissues A
Group 2
CHEM 1013	Chemistry in Life 100
CHEM 1014	Chemistry in Life 101
BIOL 1007	Molecules to Tissues A
BIOL 1012	Molecules to Tissues B

Students to choose one of the above groups for their prerequisites.

Corequisite(s)

Nil

Teaching method

Component	Duration
INTERNAL, CITY EAST
Lecture	2 x 1 hour x 13 weeks
Tutorial	2 hours x 13 weeks
Practical	4 hours x 13 weeks
Computer Practical	1 hour x 1 week

Note: These components may or may not be scheduled in every study period. Please refer to the timetable for further details.

Assessment

Examination, Test, Week 5 quiz

Fees

EFTSL*: 0.125
Commonwealth Supported program (Band 2)
To determine the fee for this course as part of a Commonwealth Supported program, go to:
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Fee-paying program for domestic and international students
International students and students undertaking this course as part of a postgraduate fee paying program must refer to the relevant program home page to determine the cost for undertaking this course.

Non-award enrolment
Non-award tuition fees are set by the university. To determine the cost of this course, go to:
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Not all courses are available on all of the above bases, and students must check to ensure that they are permitted to enrol in a particular course.

* Equivalent Full Time Study Load. Please note: all EFTSL values are published and calculated at ten decimal places. Values are displayed to three decimal places for ease of interpretation.