Cellular and Molecular Basis of Disease

Course aim

To introduce students to the concepts of tissue adaptation and reaction to disease at the cellular and molecular level and how these changes manifest as the signs and symptoms of disease.

Course content

Concepts of disease. Cell degeneration / adaptation; atrophy; hypertrophy; cell death, necrosis and apoptosis; reversible cell injury; hyperplasia, metaplasia, dysplasia.
Inflammation and repair; cell and molecular events in acute / chronic inflammation, chemical mediators of inflammation, tissue repair, pain mechanisms.
Neoplasia; cell and molecular carcinogenesis.
Circulatory and haemostasis pathology; thrombosis, embolism, infarction, circulatory shock.
Lifestyle and age related conditions.
Pathology of cardiovascular, respiratory, renal, endocrine and reproductive systems, GIT, neural and musculo-skeletal systems.
Infectious diseases, host parasite relationships. Bacterial and viral virulence factors, regulation of virulence factors, evolution of virulence. Antimicrobial agents and resistance.

Textbook(s)

Nil

Prerequisite(s)

Subject Area & Catalogue Number	Course Name
Group 1
BIOL 2035	Physiology
BIOL 2037	Immunology
BIOL 2051	Microbiology
Group 3
BIOL 2035	Physiology
BIOL 2051	Microbiology
BIOL 2057	Genes to Proteins
Group 2
BIOL 2014	Biochemistry
BIOL 2035	Physiology
BIOL 2051	Microbiology
Group 4
BIOL 2035	Physiology
BIOL 2051	Microbiology
BIOL 2016	Genetics

Students choose one of the groups above for their pre-requisite.

Corequisite(s)

Nil

Teaching method

Component	Duration
INTERNAL, CITY EAST
Lecture	2 hours x Weekly
Lecture	1 hour x Weekly
Seminar	3 hours x 3
Practical	3 hours x 9

Note: These components may or may not be scheduled in every study period. Please refer to the timetable for further details.

Assessment

Examination, Practical reports, Research assignment

Fees

EFTSL*: 0.125
Commonwealth Supported program (Band 2)
To determine the fee for this course as part of a Commonwealth Supported program, go to:
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Fee-paying program for domestic and international students
International students and students undertaking this course as part of a postgraduate fee paying program must refer to the relevant program home page to determine the cost for undertaking this course.

Non-award enrolment
Non-award tuition fees are set by the university. To determine the cost of this course, go to:
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Not all courses are available on all of the above bases, and students must check to ensure that they are permitted to enrol in a particular course.

* Equivalent Full Time Study Load. Please note: all EFTSL values are published and calculated at ten decimal places. Values are displayed to three decimal places for ease of interpretation.