Dosage Form Design 1

Course aim

To provide students with an understanding of the basis behind the formulation of solution dosage forms and to enhance students’ understanding of the relationship between structure and reactivity and how this relates to solubility and the stability of drugs and drug products.

Course content

Overview of the types of pharmaceutical products and their physical forms, how they are presented and administered, shelf-life and storage; Solution dosage forms, solubility and the process of dissolution; techniques for increasing solubility and the rate of solution; Physicochemical drug interactions and incompatibilities; Basic colligative properties and osmolarity; Electronic and structural features that influence acidity and basicity of drug molecules; buffers and ampholytes; Ionization, aqueous solubility and biological partitioning of drugs which are weak electrolytes; Structure and properties of heterocyclic drugs; Principles of quality control; Methods for the analysis of drugs; Pharmaceutical calculations.

Textbook(s)

Florence, A.T. & Attwood, D., Physicochemical Principles of Pharmacy, Current Edition, Pharmaceutical Press, London

Prerequisite(s)

Subject Area & Catalogue Number	Course Name
Group 1
CHEM 1006	Chemistry 100
CHEM 1007	Chemistry 101
Group 2
CHEM 1013	Chemistry in Life 100
CHEM 1014	Chemistry in Life 101

Students are only required to have one of the above groups for their pre-requisite.

Corequisite(s)

Nil

Teaching method

Component	Duration
INTERNAL, CITY EAST
Lecture	3 hours x 13 weeks
Tutorial	1 hour x 9 weeks
Practical	2 hours x 2 weeks
Practical	3 hours x 3 weeks

Note: These components may or may not be scheduled in every study period. Please refer to the timetable for further details.

Assessment

Examination, Practical Portfolio, Quiz

Fees

EFTSL*: 0.125
Commonwealth Supported program (Band 2)
To determine the fee for this course as part of a Commonwealth Supported program, go to:
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Fee-paying program for domestic and international students
International students and students undertaking this course as part of a postgraduate fee paying program must refer to the relevant program home page to determine the cost for undertaking this course.

Non-award enrolment
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Not all courses are available on all of the above bases, and students must check to ensure that they are permitted to enrol in a particular course.

* Equivalent Full Time Study Load. Please note: all EFTSL values are published and calculated at ten decimal places. Values are displayed to three decimal places for ease of interpretation.