Pharmacokinetic-Pharmacodynamic Modelling

Course aim

To introduce students to the concept of mathematical modelling in pharmacokinetics and pharmacodynamics, its role in understanding patient response to drug treatment and to illustrate how this information can be used to inform decisions during drug development programs.

Course content

The theoretical aspects pharmacokinetic and pharmacodynamic modelling of in vivo and in vitro data; Linear and Nonlinear models, compartmental modelling and non-compartmental analysis of pharmacokinetic data, empirical and physiological models, population models; Selection and validation of models, and their use to simulate outcomes which will assist in future study design; Methods employed to identify factors which might explain variability in drug response between individuals and how these can be incorporated into a model; Use of models to inform decisions during drug development programs.

Textbook(s)

Nil

Prerequisite(s)

Common to all relevant programs
Subject Area & Catalogue Number	Course Name
PHAR 2006	Pharmacokinetics and Biopharmaceutics P 201

Corequisite(s)

Nil

Teaching method

Component	Duration
INTERNAL, CITY EAST
Lecture	1 hour x 13 weeks
Computer Practical	2 hours x 13 weeks

Note: These components may or may not be scheduled in every study period. Please refer to the timetable for further details.

Assessment

Develop a written Pharmacokinetic model, Test, Written Test

Fees

EFTSL*: 0.125
Commonwealth Supported program (Band 2)
To determine the fee for this course as part of a Commonwealth Supported program, go to:
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Fee-paying program for domestic and international students
International students and students undertaking this course as part of a postgraduate fee paying program must refer to the relevant program home page to determine the cost for undertaking this course.

Non-award enrolment
Non-award tuition fees are set by the university. To determine the cost of this course, go to:
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Not all courses are available on all of the above bases, and students must check to ensure that they are permitted to enrol in a particular course.

* Equivalent Full Time Study Load. Please note: all EFTSL values are published and calculated at ten decimal places. Values are displayed to three decimal places for ease of interpretation.