Drug Discovery
Undergraduate
Undergraduate
PHAR 2010
Undergraduate
No
101434
4.5
No
UniSA Clinical & Health Sciences
To provide a comprehensive understanding of the drug discovery process including past, current and future trends in discovery and to develop skills in designing discovery, lead optimisation and preclinical development programs.
Overview of classical drug discovery, serendipitous discovery and the changing perspectives in drug discovery; role of traditional medicine knowledge in the development of new pharmaceutical agents; identification and validation of physiological targets for drug discovery; introduction to the biochemical and molecular basis of drug action; computational data mining, rational drug design and structure activity relationships; compound selection for drug discovery; combinatorial chemistry, natural products and product extracts as chemical starting points. Radioactive, colorimetric, luminescent, fluorescent and label-free assay technologies for compound profiling; biotechnology and gene manipulation for biochemical and cell-based assay development; methods for the preclinial evaluation of drug absorption, distribution, metabolism and excretion; principles of toxicology and preclinical evaluation of drug safety; predicting the factors that may lead to the failure of a new drug candidate and maximising the chance of success; animal studies in drug discovery; case studies in drug discovery - success stories and failures.
R.G. Hill and H.P. Rang 2012, Drug Discovery and Development: Technology in Transition, Current edition, Churchill Livingstone (Elsevier)
Subject Area & Catalogue Number | Course Name |
---|---|
Group 1 | |
CHEM 1007 | Chemistry 101 |
CHEM 1006 | Chemistry 100 |
Nil
Component | Duration | ||
---|---|---|---|
INTERNAL, CITY WEST | |||
Lecture | 1 hour x 13 weeks | ||
Workshop | 1 hour x 13 weeks | ||
Tutorial | 2 hours x 13 weeks |
Note: These components may or may not be scheduled in every study period. Please refer to the timetable for further details.
Presentation, Report, Test/Quiz
EFTSL*: 0.125
Commonwealth Supported program (Band 2)
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* Equivalent Full Time Study Load. Please note: all EFTSL values are published and calculated at ten decimal places. Values are displayed to three decimal places for ease of interpretation.