Pharmacokinetics and Biopharmaceutics

Course aim

To provide students with an understanding of the processes involved in the absorption, distribution, and elimination of drugs and the manner in which these processes influence the dosage regimens of drugs.

Course content

Overview of the time-course of drugs in the body. Calculation and interpretation of pharmacokinetic parameters. Pharmacokinetic processes of absorption, distribution and clearance and their physiological determinants. Mechanisms for the genetic and environmental basis for inter-subject differences in the metabolism and transport of drugs in the body. Metabolite kinetics. Non-linear pharmacokinetics. Pharmacokinetic-pharmacodynamic relationships. Therapeutic regimens and dosage adjustments in disease states, in the young and in the elderly. Pharmacokinetic drug interactions. Bioavailability and bioequivalence. Evaluation of the biopharmaceutical performance of dosage forms.

Textbook(s)

Tozer TN, Rowland M. 2006, Introduction to Pharmacokinetics and Pharmacodynamics, 1, Williams and Wilkins

Prerequisite(s)

Specific program
Program	Subject Area & Catalogue Number	Course Name
IBPA	BIOL 1007	Molecules to Tissues A
IBPA	BIOL 1012	Molecules to Tissues B
IBPH	BIOL 1049	Human Physiology 100
IBPH	BIOL 1050	Human Physiology 101

Corequisite(s)

Nil

Teaching method

Component	Duration
INTERNAL, CITY EAST
Lecture	3 hours x 13 weeks
Tutorial	1 hour x 13 weeks

Note: These components may or may not be scheduled in every study period. Please refer to the timetable for further details.

Assessment

Test, Written examination

Fees

EFTSL*: 0.125
Commonwealth Supported program (Band 2)
To determine the fee for this course as part of a Commonwealth Supported program, go to:
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Fee-paying program for domestic and international students
International students and students undertaking this course as part of a postgraduate fee paying program must refer to the relevant program home page to determine the cost for undertaking this course.

Non-award enrolment
Non-award tuition fees are set by the university. To determine the cost of this course, go to:
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Not all courses are available on all of the above bases, and students must check to ensure that they are permitted to enrol in a particular course.

* Equivalent Full Time Study Load. Please note: all EFTSL values are published and calculated at ten decimal places. Values are displayed to three decimal places for ease of interpretation.